BHAKTA KAVI NARSINH MEHTA UNIVERSITY

Faculty of Department

Dr. NAVAL P. KAPURIYA Associate Professor
Qualification	M.Sc., Ph.D., Post-doctorate
Specialization	Organic and Medicinal Chemistry
Area of Research/Interest	Design and development of anticancer agents
Teaching Experience	12 years
Total Research
Website / Blog
Email	navalkapuriya@bknmu.edu.in

BOOKS

SR NO.	BOOK TITLE	PUBLISHER	PUBLISH YEAR	ISBN NUMBER
1	Anticancer Agent-I: Chemistry of Bifunctional DNA alkylating agents	Lambart Publication	2018	978-613-8-26891-8
2	Anticancer Agent-I: Chemistry of Bifunctional DNA alkylating agents	Lambart Publication	2018	978-613-8-38863-0

RESEARCH PAPER

SR NO	TITLE OF PAPER	AUTHORS	JOURNAL NAME
1	Design, Synthesis and Antidiabetic Activity of Biphenylcarbonitrile-Thiazolidinedione Conjugates as Potential α-Amylase Inhibitors	Chirag H. Rathod, Pankajkumar B. Nariya, Deepika Maliwal, Raghuvir RS Pissurlenkar, Naval P. Kapuriya, and Anilkumar S. Patel	ChemistrySelect
2	Organocatalyzed Kabbe condensation reaction for mild and expeditious synthesis of 2,2-dialkyl and 2-spiro-4-chromanones	Naval P. Kapuriya, Jasmin J. Bhalodia, Mrunal A. Ambasana, Rashmi B. Patel, Atul H. Bapodra	Journal of Heterocyclic Chemistry
3	Facile Synthesis of (E)-5-Styrylpyrimidines via Wittig Reaction Using Sodium Tripolyphosphate in Water	Anilkumar S. Patel, Sahaj A. Gandhi, Rajesh D. Modh, Urmila H. Patel, Yogesh T. Naliapara	Letters in Organic Chemistry
4	Triethanolamine-catalyzed expeditious and greener synthesis of 2-amino-4H-chromenes	Anilkumar S. Patel, Satishkumar D. Tala, Pankajkumar B. Nariya, Kartik D. Ladv	Journal of Chinese Chemical Society
5	Etidronic acid catalyzed simple, facile and generalized synthetic protocol for preparation of 2-substituted-1H-benzo[d]imidazole-6-carboxylates	Pratik A. Ambasana, Naval P. Kapuriya, Pankajkumar B. Nariya, Yogesh T. Naliyapara, Rajesh G. Vaghasiya, Anilkumar S. Patel	Chemistry & Biology Interface
6	A Concise [3 3] Heteroaromatization Synthetic Strategy Afford Dicarboxamide Functionalized Novel Pyrazolo[1,5-a]pyrimidines	Anilkumar S. Patel, Naval P. Kapuriya, Yogesh T. Naliapara	Journal of Heterocyclic Chemistry
7	An improved assay method for the estimation of ticagrelor hydrochloride by reverse phase liquid chromatography	M. A. Ambasana, N. P. Kapuriya, K. M. Mangtani and K. D. Ladva	International Journal of Pharmaceutical Sciences & Research (IJPSR)
8	Exploitation of the Ability of γ-Tocopherol to Facilitate Membrane Co-localization of Akt and PHLPP1 to Develop PHLPP1-Targeted Akt Inhibitors	Dr Ribai Yan, Hsiao-Ching Chuang, Naval Kapuriya, Chih-Chien Chou, Po-Ting Lai, Hsin-Wen Chang, Chia-Ning Yang, Samuel K. Kulp, and Ching-Shih Chen	Journal of Medicinal Chemistry
9	a TBK1 inhibitor, exhibits antitumor activity in human oral squamous cell carcinoma through apoptosis induction and mitotic phase arrest	Li-Yuan Bai, Chang-Fang Chiu, Naval P. Kapuriya, Tzong-Ming Shieh, Yu-Chen Tsai, Chia-Yung Wu, Aaron M.Sargeant, Jing-Ru Weng. BX795	European Journal of Pharmacology
10	Design and synthesis of novel anti-tuberculosis agents from the celecoxib pharmacophore	Santosh B. Salunke Abul K. Azad, Naval P. Kapuriya, Joan-Miquel, Balada-Llasat, Preeti Pancholi, Larry S. Schlesinger, Ching-Shih Chen	Bioorganic and Medicinal Chemistry
11	Water Mediated Synthesis of N'-Arylmethylene-4,5,6,7-tetrahydro-2H-indazole-3-carbohydrazide Library	Mahesh M. Savant, Akshay M. Pansuriya, Chirag V. Bhuva, Naval Kapuriya, and Yogesh T. Naliapara	Organic Chemistry International
12	Development and validation of a UV spectrophotometric method for the determination of ticagrelor in bulk form	Mrunal A. Ambasana, Naval P. Kapuriya, Nilkanth J. Faldu, Kartik D. Ladva	Der Pharmacia Lettre
13	Antitumor effect of BI-D1870 on human oral squamous cell carcinoma	Chang-Fung Chiu, Li-Yuan Bai, Naval Kapuriya, Shih-Yuan Peng, Chia-Yung Wu, Aaron M. Sargeant, Michael Yuanchien Chen, Jing-Ru Weng	Cancer Chemother Pharmacol
14	Vitamin E facilitates the inactivation of the kinase AKT by the phosphatase PHLPP1	Po-Hsien Huang, Hsiao-Ching Chuang, Chih-Chien Chou, Huling Wang, Su-Lin Lee, Hsiao-Ching Yang, , Hao-Che Chiu, Naval Kapuriya, Dasheng Wang Samuel K. Kulp, Ching-Shih Chen	Science Signaling
15	Development of p21 Activated Kinase-targeted Multikinase Inhibitors that Inhibit Thyroid Cancer Cell Migration	Yihui Ma, Samantha K. McCarty, Naval Kapuriya, Victoria Brendel, Chaojie Wang, Motoyasu Saji, Xiaoli Zhang, David Jarjoura, Ching-Shih Chen, Mathew D. Ringel	Journal of Clinical Endocrinology & Metabolism
16	Differential anti-proliferative activities of poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer cells	Hsiao-Ching Chuang, Naval Kapuriya, Samuel K. Kulp, Ching-Shih Chen, and Charles L. Shapiro	Breast Cancer Research and treatment
17	Fuller’s earth catalyzed a rapid synthesis of Bis(indolyl)methanes under solvent free condition	Naval Kapuriya, Rajesh Kakadiya, Mahesh M. Savant, Akshay M. Pansuriya, Chirag V. Bhuva, Jyoti Singh, Anil S. Patel, Piyush V. Pipaliya, Vipul B. Audichya, Sarala Gangadharaiah, Sridhar M. Anandalwar, Javaregowda S. Prasad, Anamik Shah,Yogesh Naliapara	Indian Journal of Chemistry
18	Development of Novel Antibacterial agents against methicillin-resistant staphylococcus aureus	Hao-Chieh Chiu, Su-Lin Lee, Naval Kapuriya, Dasheng Wang, Sung-Liang Yu, Samuel K. Kulp, Lee-Jeng Teng, Ching-Shih Chen	Bioorganic and Medicinal Chemistry
19	Design, Synthesis and Biological evaluation of Novel water-soluble N-mustards as potential anticancer agents	Naval Kapuriya, Rajesh Kakadiya, Huajin Dong, Amit Kumar, Pei-Chih Lee, Xiuguo Zhang, Ting-Chao Chou, Ching-huang Chen, King-Lam, Bhavin Marvaniya, Anamik Shah, and Tsann-Long Su	Bioorganic and Medicinal Chemistry
20	Novel Bifunctional Alkylating Agents, 5,10-dihydropyrrolo[1,2,-b]isoquinoline derivatives, synthesis and biological activity	Ravi Chaniyara, Naval Kapuriya, Huajin Dong, Pei-Chih Lee, sharda suman, Bhavin Marvaniya, Ting-Chao Chou, Te-Chang Lee, Rajesh Kakadiya, Anamik Shah and Tsann-Long Su	Bioorganic and Medicinal Chemistry
21	A concise synthetic strategy to functionalized chromenones via [5 1] heteroannulation and facile C-N/C-S/C-O bond formation with various nucleophiles	Mahesh M. Savant, Neetha Gowda, Akshay M. Pansuriya, Chirag V. Bhuva, Naval Kapuriya, Sridhar M. Anandalwar, Shashidhara J. Prasad, Anamik Shah, Yogesh T. Naliapara	Tetrahedron Letters
22	Construction of 3,4-dihydro-1,2-diazete ring through 4p electron cylization of 4-Hydroxy-2-oxo-2H Chromene-3-carbaldehyde [(1E)-aryl mehtylene] Hydrazone	Akshay M. Pansuriya, Mahesh M. Savant, Chirag V. Bhuva, Jyoti Singh, Naval Kapuriya, Yogesh T. Naliapara	Journal of Heterocyclic Chemistry
23	Water Mediated Construction of Trisubstituted Pyrazoles/Isoxazoles Library Using Ketene Dithioacetals	Mahesh M. Savant, Akshay M. Pansuriya, Chirag V. Bhuva, Naval Kapuriya, Anil S. Patel, Vipul B. Audichya, Piyush V. Pipaliya, and Yogesh T. Naliapara	Journal of Combinatorial Chemistry
24	Cation Exchange Resin (Indion 130): An Efficient, Environment Friendly and Recyclable Heterogeneous Catalyst for the Biginelli Condensation	Akshay M. Pansuriya, Mahesh M. Savant, Chirag V. Bhuva, Naval Kapuriya, Jyoti Singh, Yogesh T. Naliapara	Letters in Organic Chemistry
25	Novel DNA-directed alkylating agents: design, synthesis and potent antitumor effect of phenyl N-mustard-9-anilinoacridine conjugates via a carbamate or carbonate linker	Naval Kapuriya, Kalpana Kapuriya, Huajin Dong, Xiuguo Zhang, Ting-Chao Chou, Yu-Ting Chen, Te-Chang Lee, Wen-Chuan Lee, Tung-Hu Tsai, Yogesh Naliapara and Tsann-Long Su	Bioorganic and Medicinal Chemistry
26	A new and efficient catalyst for the synthesis of novel 5-nitro-3,4-dihydropyrimidine-2(1H)-ones	Mahesh M. Savant, Akshay M. Pansuriya, Chirag V. Bhuva, Naval Kapuriya, Yogesh T. Naliapara, Etidronic acid	Catalysis letters
27	Potent Antitumor Bifunctional DNA Alkylating Agents, Synthesis and Biological Activities of 3a-Aza-cyclopenta[a]indene	Rajesh Kakadiya, Huajin Dong, Pei-Chih Lee, Naval Kapuriya, Xiuguo Zhang, Ting-Chao Chou, Te-Chang Lee, Kalpana Kapuriya, Anamik Shah and Tsann-Long Su	Bioorganic and Medicinal Chemistry
28	Synthesis and In Vitro Cytotoxicity of 9-Anilinoacridines Bearing N-mustard Residue on Both Anilino and Acridine Rings	Ching-Huang Chen, Yi-Wen Lin, Xiuguo Zhang, Ting-Chao Chou, Tsong-Jen Tsai	European Journal of Medicinal Chemistry
29	Synthesis and Biological Activity of Stable and Potent Antitumor Agents, Aniline Nitrogen Mustards Linked to 9-Anilinoacridines via a Urea Linkage	Naval Kapuriya, Kalpana Kapuriya, Xiuguo Zhang, Ting-Chao Chou, Rajesh Kakadiya, Yu-Tse Wu, Tung-Hu Tsai, Yu-Ting Chen, Te-Chang Lee, Anamik Shah, Yogesh Naliapara and Tsann-Long Su	Bioorganic and Medicinal Chemistry
30	Novel Oxidative Nitrogen to Carbon Rearrangement Found in the Conversion of Anilines to Benzaldoximes by Treating with HCHO/H2O2	Naval Kapuriya, Kalpana Kapuriya, Narsinh M. Dodia, Yi-Wen Lin, Rajesh Kakadiya, Chao-Ting Wu, Ching-Huang Chen, Yogesh Naliapara and Tsann-Long Su	Tetrahedron Letters

PROGRAMME ATTENDED

SR NO	PROGRAMME NAME	TITLE	LEVEL OF PROGRAMME	FROM DATE	TO DATE	ORGANIZED BY	ROLE OF FACULTY
1	Orientation Programme	Programme for Faculty in Universities/College/Institute of Higher Education	National	4-Jun-20	1-Jul-20	Teaching and Learning Centere, Ramanuj College, University of Delhi in asscociation of Ministry of Human Resources, Government of India	Participeted
2	Faculty Devlopment Programme	Faculty Devlopment Programme on Curriculam Devlopment	National	19-May-20	26-May-20	Jointly Organized by HRDC Savitribai Phule Pune University (Pune) and Children's University (Gandhinagar)	Participeted
3	Workshop	Computer Aided Drug Discovery and Microbiome Analysis	National	31-Mar-19	31-Mar-19	Bioinformatics and Supercomputer Facility, Department of Bioscience, VNSGU, Surat	Participeted
4	Faculty Devlopment Programme	FDP on' Preparation of Research Proposal'	University	28-Jan-19	28-Jan-19	Bhakta Kavi Narsinh Mehta University	Attended
5	Conference	Trends in Chemical and Biological Science	International	12-Jan-19	14-Jan-19	Indian Soc. Of Chemist and Biologist, Lucknow-Uttar Pradesh	Presented
6	Conference	Frontier research in chemistry and biology interface-International conference 24th-ISCB-2018	International	1/11/2018	1/13/2018	Manipal University-Jaipur & ISCB-Lucknow, India	Presented
7	Conference	International conference Organized by Indian Society of Chemist & Biologis	International	2/6/2016	2/8/2016	Uka Tarsadia University, Surat	Presented
8	Conference	31st Conference of Indian Council of Chemist	National	12/26/2012	12/28/2012	Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India	Presented
9	Conference	Conference of American Association of Cancer Research	International	Apr-11	Apr-11	American Association of Cancer Research	Presented
10	Conference	Conference of American Association of Cancer Research	International	Apr-09	Apr-09	American Association of Cancer Research	Presented
11	Symposium	Medicinal Chemistry		3/4/2009	3/6/2009	Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India	Presented
12	Symposium	PST Medicinal Chemistry		4/25/2008	4/27/2008	Si-Tou, Taiwan	Presented
13	Conference	Conference of American Association of Cancer Research	Inertnational	Apr-08	Apr-08	American Association of Cancer Research	Presented
14	Symposium	TPA Medicinal Chemistry		5/18/2007	5/20/2007	Si-Tou, Taiwan	Presented
15	Conference	Conference of American Association of Cancer Research	Inertnational	Apr-07	Apr-07	American Association of Cancer Research	Presented

PAPER PRESENTED

SR NO	PROGRAMME NAME	TITLE	LEVEL OF PROGRAMME	ORGANIZATION	DATE
1	Trends in Chemical and Biological Science	Design Synthesis and anti-prostate Cancer activity of novel N-aryl indoles	International	Indian Soc. Of Chemist and Biologist, Lucknow-Uttar Pradesh	12-Jan-19
2	Frontier research in chemistry and biology interface-International conference 24th-ISCB-2018	· Triethanolamine catalyzed expeditious and greener synthesis of 2-amino-4H-chromenes	International	Manipal University-Jaipur & ISCB-Lucknow, India	1/11/2018
3	International conference Organized by Indian Society of Chemist & Biologis	Development of Vitamin E derivatives as AKT-inhibitors and anticancer agents	International	Uka Tarsadia University, Surat	2/6/2016
4	31st Conference of Indian Council of Chemist	Design Synthesis and Biological Evaluation of novel Vitamin E derivatives as Potential Anticancer Agents	National	Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India	12/26/2012
5	Conference of American Association of Cancer Research	Energy restriction-mimetic agents (ERMAs) decrease BRCA1 expression levels in triple-negative breast cancer cells: Arationale for combining ERMAs with poly(ADPribose) polymerase	Inertnational	American Association of Cancer Research	Apr-11
6	Conference of American Association of Cancer Research	Complete xenograft tumor remission by N-mustard-9-anilinoacridine conjugates having a carbamate or carbonate linker	Inertnational	American Association of Cancer Research	Apr-09
7	Medicinal Chemistry	Design and Synthesis of Antitumor Activity of DNA-alkylating agents	National	Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India	3/4/2009
8	PST Medicinal Chemistry	Novel Oxidative Nitrogen to Carbon Rearrangement Found in the Conversion of Anilines to Benzaldoximes by Treating with HCHO/H2O2	National	Si-Tou, Taiwan	4/25/2008
9	Conference of American Association of Cancer Research	Potent bifunctional DNA alkylating agents, derivatives of 3a-aza-cyclopenta[a]indenes against human solid tumor xenografts	Inertnational	American Association of Cancer Research	Apr-2008
10	TPA Medicinal Chemistry	Design and Synthesis of Potent Antitumor Agents, Aniline N-mustard Linked to 9-Anilinoacridines via a Urea Spacer	National	Si-Tou, Taiwan	5/18/2007
11	Conference of American Association of Cancer Research	Potent therapeutic effects of novel DNA-targeted alkylating agents, aniline N-mustards linked to DNA-affinic molecules against human tumor xenografts	Inertnational	American Association of Cancer Research	Apr-2007

SPECIAL ACADEMICS DISTINCTIONS

SR NO	ACHIEVEMENT / AWARD	MONTH YEAR
1	Discovered a novel rearrangement which give provided direct synthesis of aldoximes from amines	Dec-20
2	Invited Talk: National Seminar, organized by Tolani College of Arts and Science, Bhuj	Feb-20
3	Key note speaker: National Seminar, organized by Subhas Academy, Junagadh	Jan-19
4	Invited Talk: National Conference, organized by C. U. Shah Science College, Ahmedabad	Dec-18
5	Invited Talk: International conference at Academia Sinica, Taiwan	Jun-18
6	Invited Talk: International Conference, organized by Municipal Science College, Mahesana	Sep-17
7	Invited Talk: International conference ISCB-2011 at Saurashtra University, Rajkot	Jul-11
8	Post-Doctoral Fellowship by Ohio State University USA	Sep-12
9	Doctoral Fellowship by Institute of Biomedical Sciences, Academic Sinica, Taiwan	May-09

COLLABORATIONS

SR NO	COLLABORATION NAME	ORGANIZATION NAME	YEAR
1	Visit, Training and Placement	SNJ Labs Pvt. Ltd. Rajkot	2019
2	Collaborative research & Placement	Oxygen Healthcare Pvt. Ltd, Ahmedabad	2019
3	Provide Chemical Analysis, Support Research activity	Department of Chemistry, Atmiya University	2018

CONSULTANCY

SR.NO	PROJECT TITLE	ORGANIZATION NAME	COMPANY NAME	YEAR

BHAKTA KAVI NARSINH MEHTA UNIVERSITY, JUNAGADH

BHAKTA KAVI NARSINH MEHTA UNIVERSITY, JUNAGADH

Faculty of Department

Dr. NAVAL P. KAPURIYA

Associate Professor

navalkapuriya@bknmu.edu.in

BHAKTA KAVI NARSINH MEHTA UNIVERSITY, JUNAGADH

BHAKTA KAVI NARSINH MEHTA UNIVERSITY, JUNAGADH

Department of Chemistry and Forensic Science

Faculty of Department

Dr. NAVAL P. KAPURIYA

Associate Professor

navalkapuriya@bknmu.edu.in